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What Is The Prognosis For DCIS, High Grade Comedo And Cribriform

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Posted on Fri, 7 Jan 2022
Question: I have been dx with DCIS, high grade comedo and cribiform. Also ER and PR -0 negative. If my cells are not ER receptive then what tx will I receive.
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Answered by Dr. Dr. Muhammad Sareer Khalil (1 hour later)
Brief Answer:
Lumpectomy with radiation

Detailed Answer:

Hello,

DCIS (Ductal Carcinoma InSitu) is the presence of abnormal neoplastic cells inside a milk duct in the breast. It has a low risk of becoming invasive and is considered early form of breast cancer.


Surgery (lumpectomy) is required in most cases. Mastectomy, or removal of the breast, is recommended in some cases. After surgery, hormonal therapy may be recommended if the DCIS is hormone-receptor-positive. But since you are not positive for ER or PR then it won't be required. Lumpectomy is followed by radiation treatment for DCIS.

These are the basic guidelines and treatment options / decisions may differ for individual patients.

Let me know if you have any queries

Wishing you best of health

Thanks
Note: Hope the answers resolves your concerns, however for further guidance of skin related queries consult our Dermatologist.Click here to book a consultation
Above answer was peer-reviewed by : Dr. Remy Koshy
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Answered by
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Dr. Dr. Muhammad Sareer Khalil

General & Family Physician

Practicing since :2012

Answered : 2906 Questions

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What Is The Prognosis For DCIS, High Grade Comedo And Cribriform

Brief Answer: Lumpectomy with radiation Detailed Answer: Hello, DCIS (Ductal Carcinoma InSitu) is the presence of abnormal neoplastic cells inside a milk duct in the breast. It has a low risk of becoming invasive and is considered early form of breast cancer. Surgery (lumpectomy) is required in most cases. Mastectomy, or removal of the breast, is recommended in some cases. After surgery, hormonal therapy may be recommended if the DCIS is hormone-receptor-positive. But since you are not positive for ER or PR then it won't be required. Lumpectomy is followed by radiation treatment for DCIS. These are the basic guidelines and treatment options / decisions may differ for individual patients. Let me know if you have any queries Wishing you best of health Thanks