Brief Answer: List provided and explained Detailed Answer: Thank you for asking Miss XXXX! Akathisia is a Akathisa is one of the most common and distressing neuroleptic-induced extrapyramidal side effects from first and second generation antipsychotics. Prochlorperazine is an antipsychotic which works like a prokinetic in vomiting and vertigo etc. As you have a malignancy of Colorectal CA and you are on chemo. Usually some thing more than Prochlorperazine is needed like Ondansetron and some other options like dexamethasone, cannabinoid, Dopamine receptor antagonist,Benzodiazepines and Aprepitant. Mean while Eat small, frequent meals or snacks. Drink plenty of water and non caffeinated liquids to avoid dehydration. Avoid greasy or spicy foods. Eat dry foods such as crackers, toast, or dry cereals. Eat soft, bland foods that are easy to digest. Have a strict monitoring of electrolytes and hydration status to prevent troubles. You need a clinical dietician for your electrolytes and hydration status and a psychologist for anticipatory Nausea and vomiting and prochlorperazine replacement and an oncologist for chemo induced vomiting. Here are some suggestions for 1-Clinical dietitians Contact DC metropolitan dietitian association for better guidance. 1120 Connecticut Ave, Ste 480 Washington DC 20036 2-Psychiatrists XXXXXXX XXXXXXX XXXXXXX W XXXXXXX MD 2251 Pimmit Dr Ste C3 Falls Church, VA 22043 Tarantolo, XXXXXXX XXXXXXX Tarantolo MD 902 Pennsylvania Ave SE Washington, DC 20003 Rubinstein, Shira Shira H Rubinstein MD 8555 16th St Silver Spring, MD 20910 Ritvo, XXXXXXX XXXXXXX Z Ritvo MD 4020 XXXXXXX St Kensington, MD 20895 XXXXXXX Peggy Dominion Hospital Psychiatry 2960 Sleepy Hollow Rd Ste B Falls Church, VA 22044 3-Oncologist Rosenberg, XXXXXXX National Institute Of Health 10 Center Dr Crc Ste 3-3940 Bethesda, MD 20892 Hendricks, XXXXXXX Center For Breast Health 6410 Rockledge Dr Ste 506 Bethesda, MD 20817 Gaskins, XXXXXXX Gaskins & XXXXXXX MDs PA 7831 Belle Point Dr Greenbelt, MD 20770 Heffess, XXXXXXX XXXXXXX A Heffess MD PC 1160 Varnum St NE Ste 318 Washington, DC 20017 Green, XXXXXXX XXXXXXX George's Hosp Ctr Onclgy 3001 Hospital Dr Fl 5 Cheverly, MD 20785 I hope it helps. May the odds be ever in your favour. Khan

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Brief Answer: Mirtazapine & Benztropine Detailed Answer: Thank you for getting back to me! Akathisia is an extra pyramidal side effect of Antipsychotics the patient took for vomiting post chemo. Now the trouble of persistence of akathisia despite stopping the drug needs a bit work up to see how damaged the functions of extrapyramidal symptoms are. Benzotropines and other anticholinergics and drugs specially like Mirtazapine has shown promising effects of Mirtazapine. Instead of taking compazine 10 mg for every 6 hours she could have been advised with mornin 15 mg or it as that would have spared the odds for Akathisia. Its still manageable. get a psychiatrist and let them decide how to help it. Medicines i mentioned will be used to relieve the akathisia symptoms. Good Luck

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