
What's The Genetic Disease Risk For Children Of Related Couples?

Question: I am XXXXXXX from XXXXXXX I am 29 years old working as a software engineer . Now I am planning to marry a girl who is relative to me .She is daughter of my mothers bro. I am having so many doubts regarding that can I hat marry that girl or not. I was thinking about the future generation .So that Please suggest me
Brief Answer:
here are details
Detailed Answer:
Thanks for the query.
There are 6 percent chances of having some birth defect(related marriage) specially autosomal recesive character in comparision of 3 percent in normal population.
Some diseases like cystic fibrosis, spina bifida are 1 to 1.5 percent more likley to occur in couples which are relatives or cousines.
But nothing to worry, as the disorders may occur in normal populations also.
Age of women also carries risk of getting birth defect, like more defects in 40s than 30s.
Hope i helped you.
here are details
Detailed Answer:
Thanks for the query.
There are 6 percent chances of having some birth defect(related marriage) specially autosomal recesive character in comparision of 3 percent in normal population.
Some diseases like cystic fibrosis, spina bifida are 1 to 1.5 percent more likley to occur in couples which are relatives or cousines.
But nothing to worry, as the disorders may occur in normal populations also.
Age of women also carries risk of getting birth defect, like more defects in 40s than 30s.
Hope i helped you.
Above answer was peer-reviewed by :
Dr. Yogesh D


Thanks for giving reply sir.
So you suggested to continue right??
And I asked about Is there any needed tests before going to marriage?
Can I continue or not?
6% you said there is more possiblety na ?
Please let me knoe for these quets sir
Thank You.
So you suggested to continue right??
And I asked about Is there any needed tests before going to marriage?
Can I continue or not?
6% you said there is more possiblety na ?
Please let me knoe for these quets sir
Thank You.
Brief Answer:
continue
Detailed Answer:
Thanks for the follow up.
Yes you can do some test like genetic counselling and screening for haemoglobinopathies.
There only 3 percent extra risk becuase general people also have 3 percent risk.
So i would suggest you to go ahead after genetic counselling.
Hope i helped you.
continue
Detailed Answer:
Thanks for the follow up.
Yes you can do some test like genetic counselling and screening for haemoglobinopathies.
There only 3 percent extra risk becuase general people also have 3 percent risk.
So i would suggest you to go ahead after genetic counselling.
Hope i helped you.
Note: For detailed guidance on genetic screening consult a genetics specialist
Above answer was peer-reviewed by :
Dr. Yogesh D

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