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Which Diabetic Medication Are More Likely To Be Removed During The Dialysis Process?

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Posted on Fri, 4 Sep 2015
Question: With all the old and new insulin and oral diabetic medicines on the market today. Which diabetic medications are more likely to be removed during the dialysis process? And does it make a difference if the dialysis process is In-center hemodialysis (ICHD), Paritoneal dialysis (PD), Nocturnal dialysis (NHD) or Home hemodialysis (HHD)?
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Answered by Dr. Praveen Jeyapathy (1 hour later)
Brief Answer:
Nearly all.

Detailed Answer:
Hello. Thanks for writing to hcm. Nearly all medications are removed with dialysis and hence needs dose adjustment. The type of dialysis does not matter but hemodialysis removes the most. Glipizide and repaglinide are least affected by dialysis. Insulin levels need about 20% reduction on the days after dialysis. The safest is rapid acting analogs with basal insulin regimen. Meal time insulin doesnt vary greatly post dialysis but basal doses need reduction. Take care. Regards.
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Above answer was peer-reviewed by : Dr. Neel Kudchadkar
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Answered by
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Dr. Praveen Jeyapathy

Diabetologist

Practicing since :2005

Answered : 324 Questions

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Which Diabetic Medication Are More Likely To Be Removed During The Dialysis Process?

Brief Answer: Nearly all. Detailed Answer: Hello. Thanks for writing to hcm. Nearly all medications are removed with dialysis and hence needs dose adjustment. The type of dialysis does not matter but hemodialysis removes the most. Glipizide and repaglinide are least affected by dialysis. Insulin levels need about 20% reduction on the days after dialysis. The safest is rapid acting analogs with basal insulin regimen. Meal time insulin doesnt vary greatly post dialysis but basal doses need reduction. Take care. Regards.