Brief Answer:
Bromelain interacts with few antibiotics, anticoagulants and sedatives

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read through your query in detail.
Please find my observations below.

1. Bromelain is an enzyme preparation to treat for anti inflammatory uses and indigestion and interacts with the following antibiotics
(i) Amoxicillin
(ii) Tetracycline group including demeclocycline, minocycline and tetracycline

2. Bromelain interacts with antiplatelets or anticoagulants
These drugs include warfarin, clopidogrel and aspirin

3. Bromelain might interact with psychiatric drugs including
(i) Phenytoin and valproic acid
(ii) Barbiturates
(iii) Benzodiazepines including alprazolam and diazepam
(iv) Drugs to treat insomnia like zolpidem, zaleplon, eszopiclone and ramelteon
(v) Tricyclic antidepressants like amitriptyline
(vi) Alcohol

Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

---