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Will Depo Provera Reduce LH Hormone And Histamine In Males?

Posted on Tue, 12 Jan 2021

Question: Will depo Provera reduce LH hormone and histamine in males?

Answered by Dr. Mirjeta Guni (1 hour later)

Brief Answer:
About depo Provera relation to LH and histamine:

Detailed Answer:

Hello,

Depo provera contains medroxyprogresterone actetate that in most of the studies has resulted in decreasing LH level. Of course, it is not the appropriate treatment to lower LH but studies show that it has this effect.
Regarding to Histamine, treatment with oral medroxyprogesterone resulted in
remission of urticaria and a decrease in eosinophil counts in some patients but there are rare sporadic cases, nothing is approved.

Hope the information will help.
Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Remy Koshy

Follow up: Dr. Mirjeta Guni (19 hours later)

Thanks. So, as a male, I can use depo Provera to shut down or reduce my libido, testosterone and semen production?

Answered by Dr. Mirjeta Guni (16 hours later)

Brief Answer:
Yes, it can be used:

Detailed Answer:

Hi,

MPA is a synthetic progestin used for numerous purposes in women. When administered in males, it lowers testosterone levels, lowering sexual drive without causing feminization. It is usually safe and well tolerated.
It should of course prescribed by your physician after other alternatives are discussed.

Best wishes,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Mirjeta Guni (3 hours later)

Thanks. Also, do you recommend Degarelix 240mg (GnRH antagonist) as the best testosterone blocker quickly as compared to GnRH agonists? Thanks

Answered by Dr. Mirjeta Guni (8 hours later)

Brief Answer:
About therapy to decrease testosterone:

Detailed Answer:
Hi again,
Yes, GnRH antagonist decrease more rapidly testosterone than GnRH agonist but, differently from depo Provera, the side effects of GnRH antagonists or agonists (symptoms of low testosterone) are more attenuate than the treatment with Medroxyprogresterone.
Anyway, to start the treatment to decrease testosterone level you should be under control of endocrinologist , who will suggest the best treatment appropriate for you and will also monitor it.
Best wishes,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Mirjeta Guni (15 hours later)

Thanks. Can you please be my endocrinologist and prescribe me degarelix and monitor? I am happy to send you my recent blood work. Thanks

Answered by Dr. Mirjeta Guni (7 hours later)

Brief Answer:
See an endocrinologist in person:

Detailed Answer:

Hello,

Unfortunately it is not allowed to give online prescription.
You need to see an endocrinologist in person.

Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Mirjeta Guni (4 days later)

Thanks. I went to endocrinologist and she was not helpful at all. No one understands me. What to do? I have tried all doctors now. I don't think all doctors or endocrinologists understand and good enough to analyse different people like me. You agree? Thanks

Answered by Dr. Mirjeta Guni (13 hours later)

Brief Answer:
Transgender specialist will help;

Detailed Answer:

Hi,

You are right, cases are you are rare and I would suggest to visit a center specialized for transgender, they have experience to lower testosterone levels.

Best wishes,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Mirjeta Guni (3 hours later)

I have tried that too but no use or help. Can you please atleast write me s recommendation/referral letter or message for degarelix here? Thanks

Answered by Dr. Mirjeta Guni (19 hours later)

Brief Answer:
About degarelix prescription:

Detailed Answer:

Hello,

Degarelix is given under physician prescription only and for your indications only a transgender center can prescribe it. So, you need to find the nearest one in your area.

Regards,
Dt.Mirjeta

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Raju A.T