Question: Hi, I have GERD and likely LPR also.I would expect that a nissen fundoplication would help both the GERD and LPR correct?The LPR symptoms because in the throat and associated chronic fatigue appear more annoying than the Gerd now. Thx. XXXXXXX

Thanks for the response.Have done most lifestyle changes for awhile now but can still work on the diet i consider myself at about 80% compliance.I have not done two ppi's a day because a friend of mine has done that and now his body cannot go back to one per day.Is the double dosage of ppi to stop my current bout of esophagitis/lpr or for long term treatment?My stomach spends so much energy now digesting a small meal i can't imagine what this would be on two ppi's per day... I don't think i will be alive very long if i have to take double dose of ppi's for long term.Even on single dose for 15 years my stomach has gastritis in two places. Anyways i am scheduled for mannometry and ph study on November 4 and if no improvement by then i will try the double dose for awhile but i am so concerned about that in the long term.Don't want to go from two pills to none for five days before the test even if i can take xantac for some of that. Where do i get tested for bile reflux and what does the test consist of? Is it normal to be tired easily during a bout of esophagitis/lpr? Thx. XXXXXXX

Thanks again.I have been on ppi's for 15 years and was never able to get off them.Tried this summer over 1.5 months and gave myself esophagitis and lpr that haven;t gone away yet. My symptoms had started going downhill in early 2012 so i was referred to gastroenterologist who did endoscopy in May 2012 and found moderate esophagitis on biopsy plus chronic gastritis in 2 spots of the stomach.Biopsies on stomach,esophagus and small intestine did not reveal h. pylori and later that year i took the blowing test for h. pylori which came out negative. I also have gallstones with no bile duct dilatation noted and small hiatus hernia plus a bit of fatty liver..So what is the test you had in mind for h. pylori so that i can clear my mind of that at least.Where do i go to get the bile reflux test? You say elderly people who take ppi for years have "worsening" can you please elaborate;what do you do if they can't take the pills anymore because it seriously affect their digestive system? Should i take another blowing test for h. pylori? Thx. XXXXXXX

Thank you very much.We will see what comes out of the mannometry and ph studies and go from there.I am hoping there is long term research occurring on the effects of ppi's on the digestive process,i think it is mores serious than osteoporosis. XXXXXXX

Thank you again.I was diagnosed with small hiatal hernia about 24 years ago and i am pretty sure i was prescribed Pantoloc for 1 month following that episode.Then i had about 7-8 years pill free before i was formally declared with GERD and then took PPI's for about 15 years.My doctor told me that PPI's take away about 90% of our gastric acid secretions.I think our stomach can go by a number of years with that but after a while they have difficulty and we get told to go on the GERD diet because our stomachs no longer can digest fats/complex carbohydrates with 10% acid secretions do you agree.My stomach has been functioning quite differently for about 2 years now and cannot seem to digest the fats very well anymore.I also have way more XXXXXXX gases which i had very few before.I also have LPR and bad esophagitis.I think my body is telling me it cannot take the PPI'S very well anymore. I think 5-10 years without the pills with surgery would help me but have to go thru the mannometry/ph test next week first.It was almost a 1.5 year wait for this it's ridiculous.But i will try your double dose of ppi's after the test for awhile to see but i am afraid this may cause more gastritis or infections.Do you work in the States?

Today i started my five days without ppi's before mannometry and ph test.So i only took 2 xantacs and my energy levels are much better but esophagitis symptoms not as good.When i take ppi's i am very tired when digesting food even small light meals which form most of my diet now.I also have urinary tract sensitivity for about 1 month now and cipro antibiotic did not get rid of it.My esophagitis symptoms are always worse during the evening,how come? And you are suggesting moving to two ppi's per day versus one nexium and one xantac.I just think generally the body gets used to the new dose and then i am stuck with two pills per day that will make me even more tired at digestion and likley increase the chances of infection in the digestive system.Also my hemorroids are back even on a very good light diet.Don't you think its because the ppi's are negatively affecting the liver function? I think the nissen fundoplication may give me 5-10 years for esophagitis/lpr to recover and hopefully digestive function to slightly improve.If not i think the digestive function will continue to deteriorate same as esophagus.don't you think so?Please tell me why i would not be better with the operation even if 10% have nightmares to go through (esophagal dilatation, etc...)?At 57 years old if i wait too long i'll be too old or my symptoms too advanced for surgery correct? Thx. XXXXXXX