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Will Oxandrolone Treatment Have An Impact During Gnrh Pulse Generation?

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Posted on Tue, 7 Jan 2014
Question: i have a question. I underwent oxandrolone treatment at 14.5 years old (2.5mg daily for three months) What impact would this have had at the time on my gnrh pulse generator? Now, from studies online i read that gnrh pulses exist as young as 4 & 5 year olds....but feel maybe in my particular case, gnrh pulsality was completely shut down. And then the oxandrolone restarted my gnrh pulsality, which continued till today. Hope you can advise. Best Regards
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Answered by Dr. Arun (2 days later)
Brief Answer: short course has no significanteffect on gnrh puls Detailed Answer: Hi Thanks for writing to health care magic. Short course of oxandralone is given usually in Constitutional delay of growth and maturation. It's safe and does not affect the HPG axis. HPG is hypothalamic pituitary gonadal axis. Your Gnrh pulses would have started by 5 years but to develop secondary sexual characteristics, oxandralone helps. It shouldn't affect your Gnrh pulses . Regards Dr Arun
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Arun

Pediatrician, Pulmonology

Practicing since :2003

Answered : 1966 Questions

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Will Oxandrolone Treatment Have An Impact During Gnrh Pulse Generation?

Brief Answer: short course has no significanteffect on gnrh puls Detailed Answer: Hi Thanks for writing to health care magic. Short course of oxandralone is given usually in Constitutional delay of growth and maturation. It's safe and does not affect the HPG axis. HPG is hypothalamic pituitary gonadal axis. Your Gnrh pulses would have started by 5 years but to develop secondary sexual characteristics, oxandralone helps. It shouldn't affect your Gnrh pulses . Regards Dr Arun