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Can I Take Escitalopram With Warfarin

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Posted on Thu, 12 Mar 2020
Question: can i take escitalopram with warfarin
doctor
Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
I would recommend as follows:

Detailed Answer:
Hello!

Welcome to Ask a Doctor service!

Regarding your concern, I would explain that escitalopram can increase warfarin plasma levels, by decreasing its metabolism. This will lead in an increased risk for bleeding.

For this reason, I would recommend considering another antidepressant.

In case you decide to start escitalopram, I would recommend a close monitoring of INR levels : every 3 days in the first week of starting escitalopram, and then every week, until achieving a new balance, when the dose of escitalopram and warfarin will need no further dose adjustments.

Hope you will find this answer helpful!

I remain at your disposal for any further questions whenever you need!

Kind regards,

Dr. Ilir Sharka, Cardiologist
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (2 hours later)
What should i take? I have social anxiety!
doctor
Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
I would recommend as follows:

Detailed Answer:
Hello again!

I would recommend Amitriptyline instead, which has no interactions with warfarin.

It is important to start at a low dose and increase slowly in order to avoid possible adverse effects like dry mouth and sedation.

You should discuss this with your doctor about the above treatment option.

Hope you will find this answer helpful!

Wishing all the best,

Dr.Iliri

Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
Dr.
Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9534 Questions

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Can I Take Escitalopram With Warfarin

Brief Answer: I would recommend as follows: Detailed Answer: Hello! Welcome to Ask a Doctor service! Regarding your concern, I would explain that escitalopram can increase warfarin plasma levels, by decreasing its metabolism. This will lead in an increased risk for bleeding. For this reason, I would recommend considering another antidepressant. In case you decide to start escitalopram, I would recommend a close monitoring of INR levels : every 3 days in the first week of starting escitalopram, and then every week, until achieving a new balance, when the dose of escitalopram and warfarin will need no further dose adjustments. Hope you will find this answer helpful! I remain at your disposal for any further questions whenever you need! Kind regards, Dr. Ilir Sharka, Cardiologist