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Can I Take Prednisone , Plaquenil And Diflucan Together?

Posted on Fri, 7 Mar 2025

Question: can i take prednisone, plaquenil and diflucan together? any interactions?

Answered by Dr. Diwashish Biswas (1 hour later)

Brief Answer:
Need dose adjustment

Detailed Answer:
Hello,
I have gone through your question, I understand your concern.
Diflucan can lead to increased blood level of prednisone, so need dose adjustment.
While no issue in taking prednisone with plaquenil
I hope your query is clear now.
So if some doctor has advised you above medication, then above issue has already been taken care of, so nothing to worry about.
But if you are planning to take above medication, then need dose adjustment.
Thanks and regards
Dr Diwashish biswas

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Diwashish Biswas (6 hours later)

okay can you explain dose adjustment? should prednisone dose be lower in order to take diflucan?

Answered by Dr. Diwashish Biswas (1 hour later)

Brief Answer:
Yes

Detailed Answer:
Hello
Welcome To Ask A Doctor Service
I have gone through your question, I understand your concern.
Yes decrease the dose of prednisolone by 25 percent, if you are taking diflucan.
I hope your query is clear now.
Thanks and regards
Dr Diwashish biswas

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Above answer was peer-reviewed by : Dr. Yogesh D