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Dr Can You Have A Look
Question: dr can you have a look
dr can you have a look
Brief Answer:
Labs and examinations explained
Detailed Answer:
Hello and welcome to "Ask a Doctor" service.
I checked the uploaded tests and here is what can be seen there:
1. blood tests:
- There is a mildly elevated sugar level, if the test was not done fasting you don't need to worry about it
- There is a slight increase of creatinine which shows that your kidneys might have a little reduced function.
2. prostate scan (abdominal and pelvic scan):
- there are two lesions noticed that the examiner can not rule out that they may be cancer but the good news is that they seem limited in the prostate and they have not spread in the area around
3. Lung scan:
- there is some old lesions that the examiner is not worried about but there are a few small lesions noticed that again she can not determine the nature of them. Comparing them with previous or later scans will give more information so because you do not have previous scans she has recommended repeat of the chest scan in 3 months to monitor the behavior of these small lesions.
4. Bone scan:
- there were no lesions in the bones that would be suspicious of cancer spread in the bone
To conclude:
- you have prostate lesions that need to be further examined to identify their nature if they are cancer or not because imaging examination can not rule out that they are cancer related. The good news is though that they are confined within the prostate and do not seem to have invaded locally (found quite early)
- there does not seem to be spread in other organs or bone but a few small lung lesions that need to be followed up in time to make sure what is their nature
- there are few changes in the blood (sugar level and creatinine) but these are only mild and might just need to be followed on time.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Labs and examinations explained
Detailed Answer:
Hello and welcome to "Ask a Doctor" service.
I checked the uploaded tests and here is what can be seen there:
1. blood tests:
- There is a mildly elevated sugar level, if the test was not done fasting you don't need to worry about it
- There is a slight increase of creatinine which shows that your kidneys might have a little reduced function.
2. prostate scan (abdominal and pelvic scan):
- there are two lesions noticed that the examiner can not rule out that they may be cancer but the good news is that they seem limited in the prostate and they have not spread in the area around
3. Lung scan:
- there is some old lesions that the examiner is not worried about but there are a few small lesions noticed that again she can not determine the nature of them. Comparing them with previous or later scans will give more information so because you do not have previous scans she has recommended repeat of the chest scan in 3 months to monitor the behavior of these small lesions.
4. Bone scan:
- there were no lesions in the bones that would be suspicious of cancer spread in the bone
To conclude:
- you have prostate lesions that need to be further examined to identify their nature if they are cancer or not because imaging examination can not rule out that they are cancer related. The good news is though that they are confined within the prostate and do not seem to have invaded locally (found quite early)
- there does not seem to be spread in other organs or bone but a few small lung lesions that need to be followed up in time to make sure what is their nature
- there are few changes in the blood (sugar level and creatinine) but these are only mild and might just need to be followed on time.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Brief Answer:
Labs and examinations explained
Detailed Answer:
Hello and welcome to "Ask a Doctor" service.
I checked the uploaded tests and here is what can be seen there:
1. blood tests:
- There is a mildly elevated sugar level, if the test was not done fasting you don't need to worry about it
- There is a slight increase of creatinine which shows that your kidneys might have a little reduced function.
2. prostate scan (abdominal and pelvic scan):
- there are two lesions noticed that the examiner can not rule out that they may be cancer but the good news is that they seem limited in the prostate and they have not spread in the area around
3. Lung scan:
- there is some old lesions that the examiner is not worried about but there are a few small lesions noticed that again she can not determine the nature of them. Comparing them with previous or later scans will give more information so because you do not have previous scans she has recommended repeat of the chest scan in 3 months to monitor the behavior of these small lesions.
4. Bone scan:
- there were no lesions in the bones that would be suspicious of cancer spread in the bone
To conclude:
- you have prostate lesions that need to be further examined to identify their nature if they are cancer or not because imaging examination can not rule out that they are cancer related. The good news is though that they are confined within the prostate and do not seem to have invaded locally (found quite early)
- there does not seem to be spread in other organs or bone but a few small lung lesions that need to be followed up in time to make sure what is their nature
- there are few changes in the blood (sugar level and creatinine) but these are only mild and might just need to be followed on time.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Labs and examinations explained
Detailed Answer:
Hello and welcome to "Ask a Doctor" service.
I checked the uploaded tests and here is what can be seen there:
1. blood tests:
- There is a mildly elevated sugar level, if the test was not done fasting you don't need to worry about it
- There is a slight increase of creatinine which shows that your kidneys might have a little reduced function.
2. prostate scan (abdominal and pelvic scan):
- there are two lesions noticed that the examiner can not rule out that they may be cancer but the good news is that they seem limited in the prostate and they have not spread in the area around
3. Lung scan:
- there is some old lesions that the examiner is not worried about but there are a few small lesions noticed that again she can not determine the nature of them. Comparing them with previous or later scans will give more information so because you do not have previous scans she has recommended repeat of the chest scan in 3 months to monitor the behavior of these small lesions.
4. Bone scan:
- there were no lesions in the bones that would be suspicious of cancer spread in the bone
To conclude:
- you have prostate lesions that need to be further examined to identify their nature if they are cancer or not because imaging examination can not rule out that they are cancer related. The good news is though that they are confined within the prostate and do not seem to have invaded locally (found quite early)
- there does not seem to be spread in other organs or bone but a few small lung lesions that need to be followed up in time to make sure what is their nature
- there are few changes in the blood (sugar level and creatinine) but these are only mild and might just need to be followed on time.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Dr
is this injection is what the doctor wants to do to me the sane as which cedar sinai said the psa could spread ? is this the same injection
SEPTEMBER 5, 2018
Hormone therapy can make prostate cancer worse, study finds
by Cedars-Sinai Medical Center
Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia
Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur.
Prostate cancer is the second-leading cause of cancer death in men, behind lung cancer, killing nearly 30,000 in the U.S. each year, according to the XXXXXXX Cancer Society. In its early stages, the most common type, adenocarcinoma, is curable and generally responds well to therapies, including those that target androgen—a male sex hormone that stimulates tumor growth.
However, in certain patients, the cancer becomes resistant to androgen-targeted therapy, and the cancer recurs or spreads. One possible reason for that resistance, the study indicated, appears to be that the therapy causes some adenocarcinoma cells to become neuroendocrine cancer-type cells—a rare type that normally appears in fewer than 1 percent of prostate cancer patients.
"This transformation is a problem because neuroendocrine prostate cancer is especially aggressive, metastasizes more readily and is more resistant to both androgen-targeted therapy and chemotherapy," said XXXXXXX Bhowmick, Ph.D., co-director of the Cancer Biology Program at the XXXXXXX Oschin Comprehensive Cancer Institute at Cedars-Sinai. He is XXXXXXX author of the study, published in the Journal of Clinical Investigation, and XXXXXXX XXXXXXX Ph.D., former project scientist in his laboratory, is the lead author.
Bhowmick said about one-fourth of the patients who receive androgen-targeted therapy may relapse with tumors that show features of neuroendocrine prostate cancer and develop treatment-resistant disease, according to published research.
To learn more about this process, the investigators examined how cancer cells interact with the supporting cells near the tumor, referred to as the tumor microenvironment, in laboratory mice. They found these interactions raised the level of the amino acid glutamine, turning the supporting cells into "factories" that supplied fuel for the cancer cells.
"While glutamine is known to spur cancer growth, its role in prostate cancer cells to trigger reprogramming of adenocarcinoma cells into neuroendocrine cancer cells is a new and important finding," said XXXXXXX Gottlieb, MD, professor of Medicine and vice chair of translational medicine in the Department of Biomedical Sciences at Cedars-Sinai. Gottlieb was a co-author of the study.
The team also examined how androgen-targeted therapy affected the cancer microenvironment.
"To our XXXXXXX we found this type of therapy further changed the cellular environment in a way that caused adenocarcinoma cells in the prostate to transform into neuroendocrine cancer-type cells," said Bhowmick, professor of Medicine and Biomedical Sciences.
As the final step in validating the findings in mice, investigators compared levels of glutamine in the plasma of small groups of patients—one with treatment-responsive prostate cancer and the other with treatment-resistant prostate cancer. They found that levels of glutamine were higher in the second group.
This finding has potential implications for treating prostate cancer patients, said XXXXXXX Posadas, MD, co-director of the Translational Oncology Program at the cancer institute and associate professor and clinical chief of the Division of Hematology/Oncology in the Department of Medicine at Cedars-Sinai.
"The study raises the possibility that a simple blood test measuring glutamine might be able to pinpoint when androgen-targeted therapy is failing in a prostate cancer patient and even predict when therapy resistance will occur," said Posadas, who co-authored the study. He said the team is designing a new study to test this hypothesis.
Dr
is this injection is what the doctor wants to do to me the sane as which cedar sinai said the psa could spread ? is this the same injection
SEPTEMBER 5, 2018
Hormone therapy can make prostate cancer worse, study finds
by Cedars-Sinai Medical Center
Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia
Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur.
Prostate cancer is the second-leading cause of cancer death in men, behind lung cancer, killing nearly 30,000 in the U.S. each year, according to the XXXXXXX Cancer Society. In its early stages, the most common type, adenocarcinoma, is curable and generally responds well to therapies, including those that target androgen—a male sex hormone that stimulates tumor growth.
However, in certain patients, the cancer becomes resistant to androgen-targeted therapy, and the cancer recurs or spreads. One possible reason for that resistance, the study indicated, appears to be that the therapy causes some adenocarcinoma cells to become neuroendocrine cancer-type cells—a rare type that normally appears in fewer than 1 percent of prostate cancer patients.
"This transformation is a problem because neuroendocrine prostate cancer is especially aggressive, metastasizes more readily and is more resistant to both androgen-targeted therapy and chemotherapy," said XXXXXXX Bhowmick, Ph.D., co-director of the Cancer Biology Program at the XXXXXXX Oschin Comprehensive Cancer Institute at Cedars-Sinai. He is XXXXXXX author of the study, published in the Journal of Clinical Investigation, and XXXXXXX XXXXXXX Ph.D., former project scientist in his laboratory, is the lead author.
Bhowmick said about one-fourth of the patients who receive androgen-targeted therapy may relapse with tumors that show features of neuroendocrine prostate cancer and develop treatment-resistant disease, according to published research.
To learn more about this process, the investigators examined how cancer cells interact with the supporting cells near the tumor, referred to as the tumor microenvironment, in laboratory mice. They found these interactions raised the level of the amino acid glutamine, turning the supporting cells into "factories" that supplied fuel for the cancer cells.
"While glutamine is known to spur cancer growth, its role in prostate cancer cells to trigger reprogramming of adenocarcinoma cells into neuroendocrine cancer cells is a new and important finding," said XXXXXXX Gottlieb, MD, professor of Medicine and vice chair of translational medicine in the Department of Biomedical Sciences at Cedars-Sinai. Gottlieb was a co-author of the study.
The team also examined how androgen-targeted therapy affected the cancer microenvironment.
"To our XXXXXXX we found this type of therapy further changed the cellular environment in a way that caused adenocarcinoma cells in the prostate to transform into neuroendocrine cancer-type cells," said Bhowmick, professor of Medicine and Biomedical Sciences.
As the final step in validating the findings in mice, investigators compared levels of glutamine in the plasma of small groups of patients—one with treatment-responsive prostate cancer and the other with treatment-resistant prostate cancer. They found that levels of glutamine were higher in the second group.
This finding has potential implications for treating prostate cancer patients, said XXXXXXX Posadas, MD, co-director of the Translational Oncology Program at the cancer institute and associate professor and clinical chief of the Division of Hematology/Oncology in the Department of Medicine at Cedars-Sinai.
"The study raises the possibility that a simple blood test measuring glutamine might be able to pinpoint when androgen-targeted therapy is failing in a prostate cancer patient and even predict when therapy resistance will occur," said Posadas, who co-authored the study. He said the team is designing a new study to test this hypothesis.
Brief Answer:
You will need a biopsy first before it is decided which is the the best treatment regimen for you
Detailed Answer:
Hello,
Thank you for the reply and the information provided.
I did not notice in your papers that you have had a biopsy examination of the lumps. Normally treatment is based on the clinical findings (the symptoms you may have), spread of the tumor, PSA level and the results of the biopsy (Gleason score).
Firstly you will need to confirm you have cancer and what degree it is. After that best treatment will be decided. Treatment can be complex and varies from just observation (in those with low risk for spread of the tumor) to surgery, radiation, chemiotherapy and hormonotherapy; it should be individualized in each patient.
The material you attached is interesting and needs to be discussed with the doctor that is planning to treat you but please be reminded that they do mention in the study that further studies have to be made to confirm these findings.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
You will need a biopsy first before it is decided which is the the best treatment regimen for you
Detailed Answer:
Hello,
Thank you for the reply and the information provided.
I did not notice in your papers that you have had a biopsy examination of the lumps. Normally treatment is based on the clinical findings (the symptoms you may have), spread of the tumor, PSA level and the results of the biopsy (Gleason score).
Firstly you will need to confirm you have cancer and what degree it is. After that best treatment will be decided. Treatment can be complex and varies from just observation (in those with low risk for spread of the tumor) to surgery, radiation, chemiotherapy and hormonotherapy; it should be individualized in each patient.
The material you attached is interesting and needs to be discussed with the doctor that is planning to treat you but please be reminded that they do mention in the study that further studies have to be made to confirm these findings.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Above answer was peer-reviewed by :
Dr. Nagamani Ng
Brief Answer:
You will need a biopsy first before it is decided which is the the best treatment regimen for you
Detailed Answer:
Hello,
Thank you for the reply and the information provided.
I did not notice in your papers that you have had a biopsy examination of the lumps. Normally treatment is based on the clinical findings (the symptoms you may have), spread of the tumor, PSA level and the results of the biopsy (Gleason score).
Firstly you will need to confirm you have cancer and what degree it is. After that best treatment will be decided. Treatment can be complex and varies from just observation (in those with low risk for spread of the tumor) to surgery, radiation, chemiotherapy and hormonotherapy; it should be individualized in each patient.
The material you attached is interesting and needs to be discussed with the doctor that is planning to treat you but please be reminded that they do mention in the study that further studies have to be made to confirm these findings.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
You will need a biopsy first before it is decided which is the the best treatment regimen for you
Detailed Answer:
Hello,
Thank you for the reply and the information provided.
I did not notice in your papers that you have had a biopsy examination of the lumps. Normally treatment is based on the clinical findings (the symptoms you may have), spread of the tumor, PSA level and the results of the biopsy (Gleason score).
Firstly you will need to confirm you have cancer and what degree it is. After that best treatment will be decided. Treatment can be complex and varies from just observation (in those with low risk for spread of the tumor) to surgery, radiation, chemiotherapy and hormonotherapy; it should be individualized in each patient.
The material you attached is interesting and needs to be discussed with the doctor that is planning to treat you but please be reminded that they do mention in the study that further studies have to be made to confirm these findings.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Above answer was peer-reviewed by :
Dr. Nagamani Ng
Dr i really don't want to do the biopsy thats why i did the other teat
Dr i really don't want to do the biopsy thats why i did the other teat
Brief Answer:
Biopsy is important to grade the tumor and decide best treatment
Detailed Answer:
Hello,
I understand your concern with having to go through an invasive procedure such as biopsy, but on the other hand if you do not have one you leave the doctor taking decisions for your health with less tools while he evaluates you and might lead him to take blind decisions for you with not necessarily the best results. According to the study you attached in the message, the patients were evaluated with biopsy related to the aggressiveness of their tumor, so they knew it was progressive or not (if it is an adenocarcinoma or a neuroendocrine cancer is information you can get only by the biopsy results). So, I would strongly encourage you to reconsider it, there are ways to help with the procedure to be comfortable.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Biopsy is important to grade the tumor and decide best treatment
Detailed Answer:
Hello,
I understand your concern with having to go through an invasive procedure such as biopsy, but on the other hand if you do not have one you leave the doctor taking decisions for your health with less tools while he evaluates you and might lead him to take blind decisions for you with not necessarily the best results. According to the study you attached in the message, the patients were evaluated with biopsy related to the aggressiveness of their tumor, so they knew it was progressive or not (if it is an adenocarcinoma or a neuroendocrine cancer is information you can get only by the biopsy results). So, I would strongly encourage you to reconsider it, there are ways to help with the procedure to be comfortable.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Above answer was peer-reviewed by :
Dr. Prasad
Brief Answer:
Biopsy is important to grade the tumor and decide best treatment
Detailed Answer:
Hello,
I understand your concern with having to go through an invasive procedure such as biopsy, but on the other hand if you do not have one you leave the doctor taking decisions for your health with less tools while he evaluates you and might lead him to take blind decisions for you with not necessarily the best results. According to the study you attached in the message, the patients were evaluated with biopsy related to the aggressiveness of their tumor, so they knew it was progressive or not (if it is an adenocarcinoma or a neuroendocrine cancer is information you can get only by the biopsy results). So, I would strongly encourage you to reconsider it, there are ways to help with the procedure to be comfortable.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Biopsy is important to grade the tumor and decide best treatment
Detailed Answer:
Hello,
I understand your concern with having to go through an invasive procedure such as biopsy, but on the other hand if you do not have one you leave the doctor taking decisions for your health with less tools while he evaluates you and might lead him to take blind decisions for you with not necessarily the best results. According to the study you attached in the message, the patients were evaluated with biopsy related to the aggressiveness of their tumor, so they knew it was progressive or not (if it is an adenocarcinoma or a neuroendocrine cancer is information you can get only by the biopsy results). So, I would strongly encourage you to reconsider it, there are ways to help with the procedure to be comfortable.
I hope this answers your query. Let me know if I can assist you further.
Regards,
Dr. Antoneta Zotaj,
General and Family Physician
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Prasad
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