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What Is The Mechanism That Amitriptyline Inhibits Some Absorption Of

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Posted on Fri, 15 Jan 2021
Question: what is the mechanism that Amitriptyline inhibits some absorption of levothyroxine?
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Answered by Dr. Dr.Dorina Gurabardhi (2 hours later)
Brief Answer:
The mechanism is explained below in details.

Detailed Answer:
Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Amytriptiline affects the thyroid function.
This medication can change the iodine capture by thyroid cells or can change iodine, making it unavailable for thyroid to produce hormones.
So, it can decrease thyroid hormone blood levels.
The same way it influences in the Levothyroxine capture,making it unavailable for the thyroid.

Hope I have answered your query. Let me know if I can assist you further.

Kind regards!

Dr.Dorina Gurabardhi
General &Family Physician
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Dr.Dorina Gurabardhi

General & Family Physician

Practicing since :2013

Answered : 13558 Questions

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What Is The Mechanism That Amitriptyline Inhibits Some Absorption Of

Brief Answer: The mechanism is explained below in details. Detailed Answer: Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Amytriptiline affects the thyroid function. This medication can change the iodine capture by thyroid cells or can change iodine, making it unavailable for thyroid to produce hormones. So, it can decrease thyroid hormone blood levels. The same way it influences in the Levothyroxine capture,making it unavailable for the thyroid. Hope I have answered your query. Let me know if I can assist you further. Kind regards! Dr.Dorina Gurabardhi General &Family Physician