My Pharmacy has changed my Percocet 10/325, which I ve taken for years and have been switched to many diff. generic manufacturers over the years. However, they have recently changed to a brand called Amneal and after only taking it for two days I have experienced symptoms I ve never had before and they are extreme nonstop exhaustion and actually waking in the middle of the day finding I just conked out for two hours after a full nights sleep. Also, as Im sitting here writing you my normal areas of pain are projecting themselves after just taking another dose 30 minutes ago. Now, the only thing different is Ive been unusually completely constipated for the last 7 days. Do you think that once my digestive trac is cleared I will react normally to my new pain med? Do you poss. recommend using an otc enema? This is very embarrassing to talk about but I have to get help and I hoped to find home relief before going to my very busy Dr. s office. What are your thoughts? Thanks, Kim