I have been using Losartan Hctz for over a year success controlling BP to about 125/65. Since the first of the year Systolic now ranges from 135 to 165, dystolic remains same (60-70). I prefer ARB to ACE, researching addition of Calcium CB. Will be talking to my DR soon about change. Exforge has many complaints (cough, tiredness), 1. Azor and 2. Twynasta seem to have fewer occurrences. I am 70, very active (cycling, XC skiing, Kayaking, sailing, running, hiking) and want any change in meds to have minimal impact on performance. Q1 Would 1 or 2 above be a reasonable replacement? Q2 Is one preferable? Q3 Comments? thanks---bruce