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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are PCR Tests Done Within 1 Year Accurate?

We are about to adopt a baby from russia, one year old. Her mother is HiV positive. The child born in 4th March 2009 had 2 Pcr tests done for HIV (July and November), both negative. (Her antibody test for HIV was positive on November). Does this mean we can be sure she is ok (since the antibodies of the mother still haven´t disappeared?). How accurate is PCR test done twice? Can the antibodies never disappear? Can the virus appear in the future because it was not found in tests?
Mon, 13 Oct 2014
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General & Family Physician 's  Response
Thanks for using HCM.
Brief answer:Yes,accurate.
Detailed answer: Antibodies from the mother in passively enter and be seen in the infant till 15-18 months.So early antibody detection in infants plays no role,which can be false positive. PCR is specific which detects the nucleic acid of the virus in the sample specimen and is enough to say that the child is devoid of the infection.Antibody response in the mother would be lifelong.But if an effective treatment is found,antibody levels may decrease and disappear.The appearance of virus is highly unlikely in the future as already two PCR turned out to be negative.Hope this information helps you.
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Are PCR Tests Done Within 1 Year Accurate?

Thanks for using HCM. Brief answer:Yes,accurate. Detailed answer: Antibodies from the mother in passively enter and be seen in the infant till 15-18 months.So early antibody detection in infants plays no role,which can be false positive. PCR is specific which detects the nucleic acid of the virus in the sample specimen and is enough to say that the child is devoid of the infection.Antibody response in the mother would be lifelong.But if an effective treatment is found,antibody levels may decrease and disappear.The appearance of virus is highly unlikely in the future as already two PCR turned out to be negative.Hope this information helps you.