Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Specific side effects of Prozac related to muscle and bodybuilding. Fatigue - Loss of normal strength so as to not be able to do the usual physical and mental activities. Hot Flashes - Brief, abnormal enlargement of the blood vessels that causes a sudden heat sensation over the entire body. Women in menopause will sometimes experience this. Leg Pain - A hurtful sensation in the legs that is caused by excessive stimulation of the nerve endings in the legs and results in extreme discomfort. Malaise - The somewhat unclear feeling of discomfort you get when you start to feel sick. Pain in limb - Sudden, sharp, and uncontrolled leg or arm discomfort. Syncope - A short period of light-headedness or unconsciousness (black-out) also known as fainting, caused by lack of oxygen to the brain because of an interruption in blood flow to the brain. Tightness of Chest - Mild or sharp discomfort, tightness or pressure in the chest area (anywhere between the throat and belly). The causes can be mild or seriously life-threatening because they include the heart, lungs and surrounding muscles. Palpitation - Unusual and not normal (abnormal) heartbeat, that is sometimes irregular, but rapid, and forceful thumping or fluttering. It can be brought on by shock, excitement, exertion, or medical stimulants. A person is normally unaware of his/her heartbeat. Hypertension - High blood pressure, a symptom of disease in the blood vessels leading away from the heart. Hypertension is known as the “silent killer.” The symptoms are usually not obvious; however, it can lead to damage to the heart, brain, kidneys and eyes, and can even lead to stroke and kidney failure. Bradycardia - The heart rate is slowed from 72 beats per minute, which is normal, to below 60 beats per minute in an adult. Tachycardia - The heart rate is sped up to above 100 beats per minute in an adult. Normal adult heart rate is 72 beats per minute. ECG Abnormal - A test called an electrocardiogram (ECG) records the activity of the heart. It measures heartbeats as well as the position and size of the heart’s four chambers. It also measures if there is damage to the heart and the effects of drugs or mechanical devices like a pacemaker on the heart. When the test is abnormal this means one or more of the following are present: heart disease, defects, beating too fast or too slow, disease of the blood vessels leading from the heart or the heart valves, and/or a past or impending heart attack. Flushing - The skin all over the body turns red. Varicose Veins - Unusually swollen veins near the surface of the skin that sometimes appear twisted and knotted, but always enlarged. They are called hemorrhoids when they appear around the rectum. The cause is attributed to hereditary weakness in the veins aggravated by obesity, pregnancy, pressure from standing, aging, etc. Severe cases may develop swelling in the legs, ankles and feet, eczema and/or ulcers in the affected areas. Constipation - Difficulty in having a bowel movement where the material in the bowels is hard due to a lack of exercise, fluid intake, and roughage in the diet, or due to certain drugs. Diarrhea - Unusually frequent and excessive runny bowel movements that may result in severe dehydration and shock. Dyspepsia/Indigestion. The discomfort one may experience after eating. It can be heartburn, gas, nausea, a bellyache or bloating. Arthralgia - Sudden sharp nerve pain in one or more joints. Arthropathy - Joint disease or abnormal joints. Arthritis - Painfully inflamed and swollen joints. The reddened and swollen condition is brought on by a serious injury or shock to the body either from physical or emotional causes. Back Discomfort - Severe physical distress in the area from the neck to the pelvis along the backbone. Hypercholesterolemia - Too much cholesterol in the blood cells. Hyperglycemia - An unhealthy amount of sugar in the blood. Increased Weight - A concentration and storage of fat in the body accumulating over a period of time caused by unhealthy eating patterns, a lack of physical activity, or an inability to process food correctly, that can predispose the body to many disorders and diseases. Joint Stiffness - A loss of free motion and easy flexibility where any two bones come together. Prozac side effects. Muscle Cramp - When muscles contract uncontrollably without warning and do not relax. The muscles of any body organs can cramp. Prozac side effects. Muscle Stiffness - The tightening of muscles making it difficult to bend. Muscle Weakness - Loss of physical strength. Myalgia - A general widespread pain and tenderness of the muscles. Thirst - A strong, unnatural craving for moisture/water in the mouth and throat. Muscle Contractions Involuntary – A spontaneous and uncontrollable tightening reaction of the muscles caused by electrical impulses from the nervous system. Muscular Tone Increased - Uncontrolled and exaggerated muscle tension. Muscles are normally partially tensed and this is what gives us muscle tone. Paresthesia - Burning, prickly, itchy, or tingling skin with no obvious or understood physical cause. Restless Legs - A need to move the legs without any apparent reason. Sometimes there is pain, twitching, jerking, cramping, burning, or a creepy-crawly sensation associated with the movements. It worsens when a person is inactive, and can interrupt sleep so one feels the need to move to gain some relief. Shaking - Uncontrolled quivering and trembling as if one is cold and chilled. Sluggishness - Lack of alertness and energy, as well as being slow to respond or perform in life. Tics - A contraction of a muscle causing a repeated movement not under the control of the person, usually on the face or limbs. Tremor - A nervous and involuntary vibrating or quivering of the body. Twitching - Sharp, jerky and spastic motion, sometimes with a sharp sudden pain. Hope I have answered your query. Let me know if I can assist you further.