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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Glipizide Without The ER Cause Blood Sugar To Plummet?

My sister-in-law is diabetic they had her onGlipizide ER 10mg one time a day, pharmacy refilled her RX but it is Glipizide 10 mg without the ER. She took it and her blood sugar went from 105 to 45 quickly. The pharmacy is closed for holiday, should she stop taking med until she can get RX changed
Mon, 18 Sep 2017
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Internal Medicine Specialist,  's  Response
Hi,

Thanks for the query.

Glipizide ER (extended release) is formulated so that the drug is released slowly over time compared to immediate release Glipizide. You can split Glipizide 10 mg (without ER) in half and can take a half (5 mg) tablet 2 times a day (every 12 hrs). But, as soon as possible, please visit a pharmacy and change your current tablets for Glipizide ER and continue taking it as prescribed (10 mg/ 1 time a day ).

I hope I have answered your question. Please, feel free to ask me more in HCM if there is anything else you need to know.

Thank you,
Dr.Malik
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Can Glipizide Without The ER Cause Blood Sugar To Plummet?

Hi, Thanks for the query. Glipizide ER (extended release) is formulated so that the drug is released slowly over time compared to immediate release Glipizide. You can split Glipizide 10 mg (without ER) in half and can take a half (5 mg) tablet 2 times a day (every 12 hrs). But, as soon as possible, please visit a pharmacy and change your current tablets for Glipizide ER and continue taking it as prescribed (10 mg/ 1 time a day ). I hope I have answered your question. Please, feel free to ask me more in HCM if there is anything else you need to know. Thank you, Dr.Malik