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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Use Symbicort Turbuhaler During Pregnancy?

I’m 6 weeks pregnant. I’m have been using Symbicort turbuhaler prescribed by my lungs specialist for mild wheezing. I asked her if I can use it when TRYING TO CONCEIVE. She said yes. There’s no connection. You can use it. Now pls confirm if I can use it during 1st trimester of pregnancy?
Thu, 18 Jan 2024
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General & Family Physician,  's  Response
Hi,

Though the studies in rats shows, that use of Symbicort is teratogenic and embryogenic, when used by oral routes. However, there is no such effects seen in rats, when used by inhalation even with very very higher doses to the tune of 300-500 times, being used in human patients.

Also, it is well known, that teratogenic effect in rats is much more than human being. No, teratogenic or embryogenic effect has been seen in human being, when Symbicort is being used thru inhalation route. Therefore, it is to be presumed as a safe drug for being used during pregnancy by inhalation route.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Satnarain Bansal, General & Family Physician
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Can I Use Symbicort Turbuhaler During Pregnancy?

Hi, Though the studies in rats shows, that use of Symbicort is teratogenic and embryogenic, when used by oral routes. However, there is no such effects seen in rats, when used by inhalation even with very very higher doses to the tune of 300-500 times, being used in human patients. Also, it is well known, that teratogenic effect in rats is much more than human being. No, teratogenic or embryogenic effect has been seen in human being, when Symbicort is being used thru inhalation route. Therefore, it is to be presumed as a safe drug for being used during pregnancy by inhalation route. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Satnarain Bansal, General & Family Physician