Hello, and I hope I can help you today. Garcinia Cambogia is a supplement, so it is not tested for interactions with other drugs like prescription medications are. So there is no evidence that taking the supplement while on Methotrexate is harmful. I want to strongly caution you against exercise though, especially if it has been less than a week since you were diagnosed with an ectopic pregnancy. Ectopic pregnancies can still rupture after a methotrexate injection, so the straining of your abdomen during vigorous exercise could possible traumatize your swollen tube. You can bleed heavily internally and could need emergency surgery if your tube ruptures, and without prompt medical care some women even die from a ruptured ectopic pregnancy. So your cravings from pregnancy should dissipate as you hormone levels fall, so hopefully you will feel less hungry over time. In the meantime, you can take your supplement but please be very careful and do not do any heavy exercise until your levels have fallen. I hope I was able to adequately answer your question today and that my advice was helpful. Best wishes, Dr. Brown