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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Chemotherapy For Liver Cancer Cause Skin Infection?

My grandaughter is 9 months old and has been getting chemo for 3 months and is now being diagnosed with a severe skin infection. She had a large tumor on her liver and had half of her liver removed as well as her gallbladder. Could the chemo be the cause of her infection?
Mon, 30 Mar 2015
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Pediatrician 's  Response
chemotherapeutic agents decrease the immunity of body by depressing bone marrow function and can predispose to various skin infection .

The drugs commonly used in liver carcinoma are doxorubicin (Adriamycin), 5-fluorouracil, and cisplatin.
hand foot mouth syndrome(painful erythema (redness of the skin) of the palms and soles, with or without bullae) is associated with doxorubicin.
skin necrosis due to doxorubicin
above lesion can be secondarily infected
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Can Chemotherapy For Liver Cancer Cause Skin Infection?

chemotherapeutic agents decrease the immunity of body by depressing bone marrow function and can predispose to various skin infection . The drugs commonly used in liver carcinoma are doxorubicin (Adriamycin), 5-fluorouracil, and cisplatin. hand foot mouth syndrome(painful erythema (redness of the skin) of the palms and soles, with or without bullae) is associated with doxorubicin. skin necrosis due to doxorubicin above lesion can be secondarily infected