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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Citalopram And Nucynta Be Taken Together?

I have been prescribed nucynta for postop pain related to acl reconstruction. I take citalopram 20mg, flonase, Claritin and one aspirin per day currently to eliminate potential blood clots. I notice citalopram and nucynta are listed as a major interaction so I am concerned if I should take the 50mg tab that has been prescribed? I am intolerant to oxycodone, hydrocodone and vicadin as they give me a severe headache so the ortho said nucynta was my only other option.
Mon, 3 Feb 2014
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Addiction Medicine Specialist 's  Response
Hi,

Taking citalopram and Nucynta together is associated with the risk of developing serotonin syndrome which is a rare but serious disorder having symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. However since the dose of both citalopram and Nucynta is low in your case and since you do not have any options other than Nucynta, you can take the medicines as prescribed, while keeping a watch for any side effects. If however, your doctor prescribed Nucynta without knowing that you are on citalopram, then you should not start Nucynta without discussing this with him.

Best wishes.
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Can Citalopram And Nucynta Be Taken Together?

Hi, Taking citalopram and Nucynta together is associated with the risk of developing serotonin syndrome which is a rare but serious disorder having symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. However since the dose of both citalopram and Nucynta is low in your case and since you do not have any options other than Nucynta, you can take the medicines as prescribed, while keeping a watch for any side effects. If however, your doctor prescribed Nucynta without knowing that you are on citalopram, then you should not start Nucynta without discussing this with him. Best wishes.