Hello dear, Most of the weight gain supplements including Endura mass are prepared from herbal ingredients & do not have any side effects if taken in the optimum dose. But, before choosing any such health supplement, it is advisable to consult your family physician once. Moreover, you should not compromise on regular exercise & routine healthy food such as: 1. Consume more of natural diet like fresh fruits, green vegetables, milk, eggs, wheat, etc. 2. Avoid oily and junk food. 3. Stay away from smoking & alcohol. Despite these measures, if you experience difficulty, it will be better to rule other causes of underweight. Investigations like complete blood count, thyroid profile, estimation of blood sugar level will be helpful to rule out any chronic infection, hormonal and metabolic causes. One more thing, please do not make hurry in gaining weight or building muscles. The metabolism of the body functions at its normal rate & any measures taken to hasten up this process can be harmful. Wishing you a healthy life. Take care.