Hi, It is not safe take Oxy elite pro while on levothyroxine. Oxy elite is promoted for weight loss however the US Food and Drug Administration (FDA) is advising consumers not to purchase or use Oxy elite pro because of its safety concerns. As per the confirmed FDA laboratory analysis Oxy elite contains fluoxetine which is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed to treat depression,obsessive-compulsive disorder (OCD), and other conditions. It can cause serious side effects including suicidal thinking, abnormal bleeding, and seizures. Although there is no documented evidence of any harmful interactions between Levothyroxine and Oxy elite pro however to be on safer side it is better to avoid taking it. Levothyroxine itself may be effective in reducing your body weight so continue taking it along with regular exercise and diet to control your body weight. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician