Hi, I had a hysterectomy 12 years ago, ovaries out as well. My doctor put me on high dose oral premarin 0.625mg for 10 of those 12 years. I became concerned about being on it so long and the dose was decreased to 0.3mg. then last year (age 53) I had an episode of blurred vision and dizziness. After the work up, a stroke was ruled out and they called it either a vaso vagul episode or a TIA. Was taken off estrogen cold turkey, after a miserable time with hot flashes, I m finally slowing down and the flashes are fewer. I am having a problem now with vaginal atrophy and urinary leakage. My doctor gave me 10mcg vagifem. I haven t started using it yet. Do you think I should use it considering the backround given? If so, how long should I continue to use it before I have to stop? I am a non smoker, no history of heart disease or high blood pressure, I am over weight.