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Can Imipramine And Omeprazole Be Taken Together?
I'm 31 weeks pregnant and have been taking 50mg of Imipramine per day for over 5 years-however I went to my Dr's yesterday as I am suffering from really bad heartburn and re flux and he gave me Omeprazole 20mg. I have just read the leaflet and it makes reference to Imipramine and says it has interaction. Is this safe for me to be taking together?
Fri, 18 Jul 2014
HELLO AND WELCOME. I REALLY APPRECIATE YOUR CONCERN BECAUSE IT IS VALID. OMEPRAZOLE AFFECTS CYP1A2 HEPATIC METABOLISM AND SO HAS SIGNIFICANT INTERACTION WITH IMIPRAMINE. BOTH OMEPRAZOLE AND ESOMEPRAZOLE SHOULDNT BE USED WITH IMIPRAMINE.
INSTEAD U CAN USE PANTOPRAZOLE WHICH HAS NO INTERACTION WITH IMIPRAMINE AND IS MUCH SAFER. FOR DYSPEPSIA I WOULD ALSO ADD SUCRALFATE 5OO MG BD. THANX, HAVE A VERY NICE DAY
INSTEAD U CAN USE PANTOPRAZOLE WHICH HAS NO INTERACTION WITH IMIPRAMINE AND IS MUCH SAFER. FOR DYSPEPSIA I WOULD ALSO ADD SUCRALFATE 5OO MG BD. THANX, HAVE A VERY NICE DAY
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