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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Overpowering Odor In Urine Be Due To Intake Of Multiple Medications?

ok im on pamelor,etodolaclevothyroxine,carisoprodo,lcyclobenzaprine,butalbital,abilify,leothyroxine and since October of last year my urine has a over powering odor not like urine and im concerned if is it all this medication and have I a need to worry or the mixture of all these meds?
Mon, 27 Oct 2014
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Internal Medicine Specialist 's  Response
Hi,

Thank you for your query. I can understand your concerns.
While the odor of urine can vary somewhat, in most cases, it does not have a strong smell.
Taking some medications may alter the odor of urine.
Out of all the drugs you are taking i.e.Nortriptyline (Pamelor) ,Etodolac,
Levothyroxine,Carisoprodol ,Cyclobenzaprine,Butalbital
Abilify(Aripiprazole) ,it is Abilify (Aripiprazole) which can impart onion like smell to urine as approximately 25% of the drug gets excreted in urine (less than 1% unchanged).
Get routine urinalysis done to exclude UTI also, as in case of urinary tract infection (UTI),the urine may take on a foul-smelling odor sometimes..


Regards

Dr. T.K. Biswas M.D.
Mumbai
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Can Overpowering Odor In Urine Be Due To Intake Of Multiple Medications?

Hi, Thank you for your query. I can understand your concerns. While the odor of urine can vary somewhat, in most cases, it does not have a strong smell. Taking some medications may alter the odor of urine. Out of all the drugs you are taking i.e.Nortriptyline (Pamelor) ,Etodolac, Levothyroxine,Carisoprodol ,Cyclobenzaprine,Butalbital Abilify(Aripiprazole) ,it is Abilify (Aripiprazole) which can impart onion like smell to urine as approximately 25% of the drug gets excreted in urine (less than 1% unchanged). Get routine urinalysis done to exclude UTI also, as in case of urinary tract infection (UTI),the urine may take on a foul-smelling odor sometimes.. Regards Dr. T.K. Biswas M.D. Mumbai