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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Child Has Gray Matter Heterotropia. Treatment?

Hi Doc. Am a zambian parent with two daughters. The younger one ia aged 1 year 8 months. She has feated 3 times in three months. A day ago, she was diagnosed of GRAY MATTER HETEROTOPIA. What could be the treatment for this condition? Is it genetically enherited?, will my daugher ever get well? At the moment she is being managed with Phenobarbiton, an anti- epileptic drug. How good is this drug in this condition. Please help. I feel for my dear daughter. Joseph Mutambo Zambia, Africa.
Thu, 4 Oct 2012
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OBGYN,  's  Response
Hello there.

I can understand your concern for your baby. It is important to know whether Gray Matter Heterotopia is an isolated finding in your child or part of any other abnormality.

Remember that Gray Matter Heterotopia can be part of syndromes as well and is even associated with maternal drug intake like probably alcohol.

The fits or convulsions which you mentioned are refractory or in other words usually do not repsond to treatment with drugs. It is a permanent damage in a segment of the brain, more precisely the cortex. Surgical intervention can be done in very resistant cases.

Overall prognosis is not good. Please ask your consultant to be as frank as possible and tell you completely what he feels about your baby after a complete head to toe assessment.

Take care.
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Child Has Gray Matter Heterotropia. Treatment?

Hello there. I can understand your concern for your baby. It is important to know whether Gray Matter Heterotopia is an isolated finding in your child or part of any other abnormality. Remember that Gray Matter Heterotopia can be part of syndromes as well and is even associated with maternal drug intake like probably alcohol. The fits or convulsions which you mentioned are refractory or in other words usually do not repsond to treatment with drugs. It is a permanent damage in a segment of the brain, more precisely the cortex. Surgical intervention can be done in very resistant cases. Overall prognosis is not good. Please ask your consultant to be as frank as possible and tell you completely what he feels about your baby after a complete head to toe assessment. Take care.