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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could Darkening Of The Skin Be Due To R-cinex?

Hi Doctor,
I have been diagnosed with Tb 4 months back. Currently i am taking R-Cinex 600 empty Stomach.
i have been noticing darkening of my skin colour with due course of time. is it beacuse of drug..and if it is..then will it get fairer as it was earlier?
Is it fine to go gym and do exercise now?
Mon, 1 Sep 2014
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General & Family Physician,  's  Response
Hello
You are having tuberculosis , last 4 months but now taking R-Cinex 600 mg ( rifampicin 600 mg + isoniazide 300 mg ) .
I have noted that it is not RCINEX which is responsible for darkening of skin ( discoloration ) .
However , rifampicin causes skin reaction eosinophilia , so indirectly these two may be responsible for discoloration.
But one thing is important in Tubercular treatment .
Initially patient advised ETHAMBUTOL 800 mg for tuberculosis . This drugs causes discoloration of skin ( darkening of skin may be the cause in your case).
Yes once you will stop drugs , your color will resume same within 1-2 years.
Yes you can do hard exercise and visit gym without any risk.
Hope this will help you.
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Could Darkening Of The Skin Be Due To R-cinex?

Hello You are having tuberculosis , last 4 months but now taking R-Cinex 600 mg ( rifampicin 600 mg + isoniazide 300 mg ) . I have noted that it is not RCINEX which is responsible for darkening of skin ( discoloration ) . However , rifampicin causes skin reaction eosinophilia , so indirectly these two may be responsible for discoloration. But one thing is important in Tubercular treatment . Initially patient advised ETHAMBUTOL 800 mg for tuberculosis . This drugs causes discoloration of skin ( darkening of skin may be the cause in your case). Yes once you will stop drugs , your color will resume same within 1-2 years. Yes you can do hard exercise and visit gym without any risk. Hope this will help you.