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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could The Below Test Suggest A Lupus?

I have just rec d a positive ANA test, and have had the malar rash since January. My liver enzymes are thru the roof (AST is 93 and ALT is 112). I am type 2 diabetic - Humalog 75/25 32 units 2x daily plus 1000 mg metformin. My cbc was all within normal limits, and my RF is 10. I am told to see a rheumatologist who specializes in lupus. Do you believe I have lupus? I am terrified.
Mon, 25 May 2015
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Internal Medicine Specialist 's  Response
Hi,

Thank you for your query. I can understand your concerns.
Malar rash can be due to SLE(Systemic lupus erythematosus).
Antinuclear Antibody (ANA)     can be associted with     Other disease like rheumatoid arthritis(30-50 %).
A positive ANA test while non-specific, increases post-test probability of SLE.
Anti-double- stranded DNA(anti-ds-DNA)- more specific for the diagnosis of SLE . That will confirm Lupus.





Regards

Dr. T.K. Biswas M.D.
Mumbai
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Rheumatologist Dr. Manish Bavaliya's  Response
Hello,
Thanks for your question.

Before answering the question , i would like to know whether have you ever been had any past history of JOINT PAIN WITH MORNING STIFFNESS , ORAL ULCERS ,HAIR LOSS etc ?

Can you please upload the ANA report ?
Mild liver enzymes elevation can be due to fatty liver also.

Thank you
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Could The Below Test Suggest A Lupus?

Hi, Thank you for your query. I can understand your concerns. Malar rash can be due to SLE(Systemic lupus erythematosus). Antinuclear Antibody (ANA) can be associted with Other disease like rheumatoid arthritis(30-50 %). A positive ANA test while non-specific, increases post-test probability of SLE. Anti-double- stranded DNA(anti-ds-DNA)- more specific for the diagnosis of SLE . That will confirm Lupus. Regards Dr. T.K. Biswas M.D. Mumbai