Hi,
Since your wife relapses each time she stops medications, it must be evident to you that for the time being she cannot stop these medications without the risk of illness reappearing. She needs to be symptom free atleast for a few years continuously before the decision of stopping her medicines, can be taken. Time will decide this.
Tapering of
risperidone (sizodon) from 3 to 1mg over 5-7 months is ok. This is decided by the clinician depending on the patient's condition.
You also say that she recovers well on the medication she gets and is symptom free, that gives one a rough idea that she is on the right medication. You said she was diagnosed with depressive illness but did not mention any antidepressant in the regimen. I will not be able to comment on it till i see the patient in person.
Depressive disorder is a chronic disorder, the disease can be controlled by medications not cured. Taking medications regularly is the only way to deal with it.
There are more problematic effects on the long run if the medicines are not taken. Repeated untreated episodes of illness can cause deterioration in the patient in many aspects. When compared to this, the side effects are more manageable. Almost all medications do have side effects.
Yes risperidone can cause weight gain in patients. It is a side effect.
To ensure she takes medicines regularly, a family member will have to monitor it. There is no other way. When a person is mentally ill, they usually lose insight into their illness so you cannot expect the patient to take medicines themselves.
Hope this helps,
Dr A Rao