I am a 19 year old female who was diagnosed with ankylosing spondylitus when I was 15. My disease has progressively worsened and now affects not only the usual lower back and hips, but my fingers, shoulders, toes and jaw. I have been on voltaren, methotrexate, salyzapyrin and predisone for a roughly a year but it is not having the necessary effect. I have also had cotozone injections into my fingers, back, hips, knees and ankles, also with little of the desired effect. In a couple of weeks I shall be going on Biologics. Hopefully that will be the end of this. I would like to know what the side effects are of biologics and to what level will they affect my life. As I my doctor told me it is a mild form of chemo? Also, will this hinder my desire to travel?