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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Patients Become Immune To Antidepressant Drugs After A Period Of Time?

My Mother in law has been on anti depressant drugs from 1998 - The medications she had were - Repoise, Amixide, Qutan, Cipralex Lifodep, Rivotril etc Lonazep, - Now currently she is taking the following medicines - Venla 75, Lithosun 300, Cipralex and trapax . My question - Are antidepressant drugs taken continuosly fo more than 15 year effect the nervous system and are they harmful. Do patients become immune to the medication after a period of time
posted on Sat, 25 Jan 2014
Twitter Fri, 7 Feb 2014 Answered on
Twitter Fri, 7 Feb 2014 Last reviewed on
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Orthopaedic Surgeon,  's  Response
Hello,

I have studied your case.

Yes all these antidepressant drugs are changing chemical neurotrasmission to brain.
When taken for long period of 15 years leads to fatigue to neuro transmission.
These medication have adverse effects on nervous system and liver and kidney.

Over the period of time tolerance to these medication increase and patient become unresponsive to particular dose ,so you may need to increase dose and frequency.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Wishing you good health.

Take care.
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Do Patients Become Immune To Antidepressant Drugs After A Period Of Time?

Hello, I have studied your case. Yes all these antidepressant drugs are changing chemical neurotrasmission to brain. When taken for long period of 15 years leads to fatigue to neuro transmission. These medication have adverse effects on nervous system and liver and kidney. Over the period of time tolerance to these medication increase and patient become unresponsive to particular dose ,so you may need to increase dose and frequency. Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Wishing you good health. Take care.