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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do The Medications Need To Be Stopped Abruptly Or Gradually?

i have been prescrbed oxicontin 40 twice per day same pregabalin 350 twice per day for over 4 years, new gp has told me to stop to stop. she has also told me to stop taking my fluoxitine 40mg per day. she ignores my views that if this is needed then must be done gradually. lookaly i have some oxicontin left although when this is done i just dont know .i am beginning to feel very depressed and have a history of suicidal tendencies pls help and advice me
Mon, 27 Apr 2015
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Psychiatrist,  's  Response
Hello thanks for asking from HCM for your health related queries

I can understand your concern. You are taking Oxycodone 40, Pregabalin and Fluoxetine 40 since last 4 years. Oxycodone is an opioid drug and if you are feeling better in pain then then in my opinion the drug should be stopped. The drug should be tapered gradually and doses should be tapered by about 20% every two weeks and should be stopped completely in about 6-8 weeks. This would prevent any serious withdrawal and you can wean off the drug completely. Once you stop the Oxycodone then you can gradually reduce the doses of Pregabalin. Don't reduce the doses of both drugs simultaneously as this would be a little difficult. If your PCP is not in the same opinion then consult a psychiatrist for proper prescription and tapering of doses.

Thanks, I hope this helps you. Take care
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Do The Medications Need To Be Stopped Abruptly Or Gradually?

Hello thanks for asking from HCM for your health related queries I can understand your concern. You are taking Oxycodone 40, Pregabalin and Fluoxetine 40 since last 4 years. Oxycodone is an opioid drug and if you are feeling better in pain then then in my opinion the drug should be stopped. The drug should be tapered gradually and doses should be tapered by about 20% every two weeks and should be stopped completely in about 6-8 weeks. This would prevent any serious withdrawal and you can wean off the drug completely. Once you stop the Oxycodone then you can gradually reduce the doses of Pregabalin. Don t reduce the doses of both drugs simultaneously as this would be a little difficult. If your PCP is not in the same opinion then consult a psychiatrist for proper prescription and tapering of doses. Thanks, I hope this helps you. Take care