Hi. I have been using Fluorouracil cream 5% 2X/day (sometimes 3X if I shower mid day) for 3 weeks on an AK on my nose. I was told to expect inflammation, dry skin and peeling, but have seen no inflammation at all. I had thought the inflammation was actually necessary for the medication to work. Is it possible that it is working despite no visible evidence of inflammation (The AK itself seems to have gone from brown to red, but is smooth and does not look irritated) or is the inflammation a necessary part of the treatment. I hate to keep putting chemicals on my skin if the treatment is not working!