Dear sir , Greeting s from HCM ... i understand your problems ... may i know why you are on this drug?? but ibrutinib increase in serum creatinine is well known increase in serum glucose is less common side effect ... please meet your specialist and get investigated thoroughly... try to follow the lifestyle modifications as below .. first stay away from all the fast / processed / and fried food stuffs .. divide your meal in to 4-5 parts per day whenever you feel hungry.. add more of fiber rich food stuffs like green leafy vegetables, raw fruits.. (not juices), eat very less of carbohydrates (rice) avoid sugar completely.. take Millets and breads prepared out of it like ragi.. ragi is a very good source of calcium too...do take more of proteins ... like egg white... say no to oils and cholesterol rich food stuffs ... u can take fish (boiled) but chicken (without skin) rarely...sir, based on this you prepare your diet chart and strictly follow it ..Do exercise .. walk at least half an hour to one hour a day ... try and practice yoga and pranayama ... some aasanas are very easy to practice and also beneficial. Quit smoking and reduce your alcohol intake. Moreover, beet root juice (inorganic nitrate), olive leaves, garlic, termeric, tamarind also have proven benefits. if u can follow these (have to!!) you can definitely see difference yourself THANK YOU