I have had 4 episodes of severe chest pain...upon having an ekg, chest X-ray, and blood work, the doctor prescribe ot can meds for acid reflux. While I think that I may be experiencing some sort of digestion issue.....I now know that each episode resulted after I took 800 mg of ibuprofen. I mentioned to a nurse fri friend that I wanted to take ibuprofen but was afraid to have an attack...she said I should take it during the day with food and that perhaps the attack was a result of taking the med at night....so today I took it at lunch 600 mg and within 30 mins the pain began and lasted 2 1/2 hrs. It s like a gripping pain deep in between my breast.