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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Seroquel Cause Increased Hostility And Paranoia?

The addition of Seroquel to my boyfriends mix of medications appears to have resulted in increased hostility, anger and paranoia. He is diagnosed with DID and PTSD and has taken Lithium for some time with good results. The Seroquel was supposed to help him sleep, but has not. While I am aware of his and can usually manage his fractures, the total change in the level of hostility towards me and others close to him is ruining relationships. Is Seroquel associated with any ill effects for those with DID?
Fri, 29 Jun 2018
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Psychiatrist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

I do not think seroquel can cause paranoia or hostility in a person with DID or PTSD. Although sometime seroquel can cause delirium (acute condition) especially in elderly which could be responsible for paranoia and hostility toward family members.

I am not aware about the dose of serquel and age of the patient but if he is elderly and used very high dose possibility of delirium should be considered.


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Does Seroquel Cause Increased Hostility And Paranoia?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. I do not think seroquel can cause paranoia or hostility in a person with DID or PTSD. Although sometime seroquel can cause delirium (acute condition) especially in elderly which could be responsible for paranoia and hostility toward family members. I am not aware about the dose of serquel and age of the patient but if he is elderly and used very high dose possibility of delirium should be considered. Hope I have answered your query. Let me know if I can assist you further.