Hi. My stepson Paul has ADHD and anxiety. He claims his Vyvanse makes his anxiety worse, but I think it s really just that when his ADHD is not treated with the Vyvanse, he doesn t focus on the anxiety, or anything else. His father doesn t like any medications. Paul s behavior without the Vyvanse significantly affects all his relationships, poorly. He definitely has some conduct disorder as well. Sleep disorder. And Aspergers. Yet he is very intelligent. And, by the way, I m a doctor too. Interventional Pain and Opiate addiction.