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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Flare Up Of Vasculitis Cause Low WBC, RBC And Blood Platelet Count?

I have been diagnosed with MPA vasculitis but I assume since mine is pAnca I also have ANCA associated vasculitis. My question is, I broke out with a painful horrible rash that looked like MRSA but I was able to identify it as a vasculitis rash. The doctor treaded me with clindamycin. Into my second week of antibiotics I started having severe headaches, no known fever and vomiting which landed me in the hospital. My CBC s showed low WBC s, low RBC s, low platelets and low neutrophils. Was all this caused by a flare up of my vasculitis?
Wed, 19 Sep 2018
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Internal Medicine Specialist,  's  Response
Hi,

MPA vasculitis (Microscopic polyangiitis) is usually associated with perinuclear antineutrophil cytoplasmic antibodies (p-ANCA)in 75% cases. Neutropenia; leukopenia; thrombocytopenia are adverse effects of clindamycin.

Anemia, leukocytosis, and thrombocytosis are common features of inflammation in MPA vasculitis.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Tushar Kanti Biswas, Internal Medicine Specialist
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Does Flare Up Of Vasculitis Cause Low WBC, RBC And Blood Platelet Count?

Hi, MPA vasculitis (Microscopic polyangiitis) is usually associated with perinuclear antineutrophil cytoplasmic antibodies (p-ANCA)in 75% cases. Neutropenia; leukopenia; thrombocytopenia are adverse effects of clindamycin. Anemia, leukocytosis, and thrombocytosis are common features of inflammation in MPA vasculitis. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Tushar Kanti Biswas, Internal Medicine Specialist