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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Having Primary Biliary Cirrhosis Cause Infertility

Hi I am 38 yrs old Female and have had an ama test come back positive. I have had a liver function test which came back normal and a ferratin level of 9 but I am not anaemic. I have intermittent pruritus but I am otherwise well. I swim for 30 mins every day, walk the dog at least 1hr a day and do 1hr cardio and weights 3 times a week. I weight 8st7lb and have no other history of illness and none in my family. My husband and I have been trying to conceive for the past 6 months with no luck. Is there any reason if I do find out that I have primary biliary cirrhosis that I would not get pregnant. I have just had 21 day progesterone ovulation test which came back positive 1st time and I'm due to have a follow up blood test to check LH and FSH. I am aware that you can have PBC for years without any progression but want to know if it will interfere with conceiving? I am not taking any medication.
Fri, 23 Oct 2015
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OB & GYN Specialist,  's  Response
PBC without progression is QUITE UNLIKELY to cause infertility. As such, your age is 38 and so we advise to start diagnosis and treatment soon. So, we should not blame PBC right now. Rather we need to find out whether there is any other reason for infertility. SO, please consult infertility specialist and investigate both husband and wife (husband's semen, wife's HSG, USG, TSH, Prolactin, FSH, LH, AMH). Good luck.
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Does Having Primary Biliary Cirrhosis Cause Infertility

PBC without progression is QUITE UNLIKELY to cause infertility. As such, your age is 38 and so we advise to start diagnosis and treatment soon. So, we should not blame PBC right now. Rather we need to find out whether there is any other reason for infertility. SO, please consult infertility specialist and investigate both husband and wife (husband s semen, wife s HSG, USG, TSH, Prolactin, FSH, LH, AMH). Good luck.