Long-term frequent masturbation can lead to chronic non bacterial prostatitis. The infection can cause much pain and discomfort, such as urinary frequency and urgency, pain and burning when urinating, pain in pelvic and genital areas, etc. It s safe to masturbate 2 to 3 times a week. You don t need to worry about the bend, it won t affect the sex. What you should keep in mind is that avoiding excessive masturbation. Once noticed the symptoms of prostatitis, you should get a timely and proper medication like herbal medicine called Diuretic and Anti-inflammatory pill.