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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Medication For Typhoid Fever Have An Effect On IVF Treatment?

Hi. I had gone for hysteroscopy and laproscopy in sept.2011 two fibroid of 2cm operated . mycobacterial DNA PCR detected could finish on e month medicine in 3 months later didn t take med. Had IUI in May 2013 unsuccessful. Then in nov took med for ivf and the day ivf was to be done for 102 fever typhoid later didn t visit gynaecologist fred up of medicine what next.guide
Mon, 25 Apr 2016
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Infertility Specialist 's  Response
Hello, when dealing with fertility issues itself can be heart breaking the treatment protocols associated can make it more difficult. But having said that desire to parent a child needs a great deal of commitment and motivation from your side. Please have patience and take care of yourself before attempting for another time.
I assume you were suggested ivf when your DNA PCR test results were positive and does your tube test( hysterosalpingogram) reveal blocked tubes? If the answer to these two questions is yes, there are few things I would like to tell you.
1. DNA PCR does not reflect an ongoing TB infection in the uterus. It is more appropriate to treat when RNA PCR comes positive. But the facility to test RNA PCR is not available everywhere. Having said it is very important to finish entire course of anti TB medication as discontinuation leads to drug resistance which is a public menace and for you as well.
2. Secondly, did you mean you didn't undergo ovum pick up due to typhoid fever or is it embryo transfer. If its egg pick up, nothing can be done but you need to undergo another ivf. If it is embryo transfer and embryos are frozen, you can undergo frozen embryo transfer anytime after your endometrium is ready either naturally or with medication.
3. If your tubes are open, you can consider iui for 3 more cycles if your husband's semen analysis is normal.
4. The chances of natural conception is difficult to predict in your case as you haven't mentioned your age, duration of infertility , other issues etc..
Hope you see good days soon. Good luck.
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Does Medication For Typhoid Fever Have An Effect On IVF Treatment?

Hello, when dealing with fertility issues itself can be heart breaking the treatment protocols associated can make it more difficult. But having said that desire to parent a child needs a great deal of commitment and motivation from your side. Please have patience and take care of yourself before attempting for another time. I assume you were suggested ivf when your DNA PCR test results were positive and does your tube test( hysterosalpingogram) reveal blocked tubes? If the answer to these two questions is yes, there are few things I would like to tell you. 1. DNA PCR does not reflect an ongoing TB infection in the uterus. It is more appropriate to treat when RNA PCR comes positive. But the facility to test RNA PCR is not available everywhere. Having said it is very important to finish entire course of anti TB medication as discontinuation leads to drug resistance which is a public menace and for you as well. 2. Secondly, did you mean you didn t undergo ovum pick up due to typhoid fever or is it embryo transfer. If its egg pick up, nothing can be done but you need to undergo another ivf. If it is embryo transfer and embryos are frozen, you can undergo frozen embryo transfer anytime after your endometrium is ready either naturally or with medication. 3. If your tubes are open, you can consider iui for 3 more cycles if your husband s semen analysis is normal. 4. The chances of natural conception is difficult to predict in your case as you haven t mentioned your age, duration of infertility , other issues etc.. Hope you see good days soon. Good luck.