I have acromegalyI am on somatuline depot for igf problem. Does this cause hard stools, and constipation? I take a shot every 30 days. I also take all hormone replace. Cortisone , synthroid 3 blood pressure medicines and more. I take stool softeners every day, but it doesn t seem to help I had surgery 13 years ago, and stereotactic radiation, also. They only got 75% of the tumor. so I take the shot so my I GF level is under control. My insides are always so sore duw to the constant hard stools. Coul this be a gall bladder problem? Thank you, Judy Bocchino