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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Excessive Salivation, Lacrimation, Uncontrollable Urination, Pinpoint Pupil And Bradycardia. Taken Atropin. When Will There Be Improvement?

50 year old male libyan ptn presented to our ER drowsy and on examination Bp190/90 .the past medical history and surgical are free ,drug history also free[non alcoholic non smoker] ,on examination comp- free. after 3hours ptn start salivation,lacrimation,urination,pin pointed pupil and bradycardia.after these symptoms they start atropin 2mg/10min. for 1day then 1mg/30min.for 5days but no improvment[ there is no pralidoxime in our country] till now the ptn on atropin ,off stopped even for 2hours the symptoms restarted again,ptn on mechanical ventilation and 3times hemodialysis was done but also no improvment [RFT still high since admission],today the nineth day post admission. I asking to help us with low facility in our country.thank you so much
Wed, 12 Jun 2013
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General & Family Physician,  's  Response
Hello,
Thanks for the query to H.C.M. Forum.
Organophosphorus is the main poison which develops,
Pin point constricted pupil ( miosis),
Salivation ( drooling ),
lacrimation,
sweating,
defecation ( involuntary),
Urination ( involuntary).

I have treated so many cases and even one can think about that.
Pralidoxim don't play any role in this type of poison.
The drug is only one that ATROPINE 1ml ampoule is available (0.6 mg/ml)

Now note down very carefully 4 amp every four hours till pupil dilate , tachycardia, hot flushes, redness all over body with very high temperature, dryness of mouth, confusion, restlessness, slurred speech, staggering gait.
Now when you see all these symptoms appear , it means there is atropinization and you have to maintain this atropinization till patient don't fully recover.
Very carefully the dosage have to taper.
100 % safe and reliable treatment.
I have tried over many , many patients , but I don't have any scientific proof published.
Good luck.
Dr. HET
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Excessive Salivation, Lacrimation, Uncontrollable Urination, Pinpoint Pupil And Bradycardia. Taken Atropin. When Will There Be Improvement?

Hello, Thanks for the query to H.C.M. Forum. Organophosphorus is the main poison which develops, Pin point constricted pupil ( miosis), Salivation ( drooling ), lacrimation, sweating, defecation ( involuntary), Urination ( involuntary). I have treated so many cases and even one can think about that. Pralidoxim don t play any role in this type of poison. The drug is only one that ATROPINE 1ml ampoule is available (0.6 mg/ml) Now note down very carefully 4 amp every four hours till pupil dilate , tachycardia, hot flushes, redness all over body with very high temperature, dryness of mouth, confusion, restlessness, slurred speech, staggering gait. Now when you see all these symptoms appear , it means there is atropinization and you have to maintain this atropinization till patient don t fully recover. Very carefully the dosage have to taper. 100 % safe and reliable treatment. I have tried over many , many patients , but I don t have any scientific proof published. Good luck. Dr. HET