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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Anemia, Bradycardia. History Of Carcinoid In Stomach. How To Reduce Tumor Growth?

I am 40 Yrs old. Diagnosed @ 30 Yrs. for Aneamic, done blood transmission, diagnosed Bradycardia. Implanted Dual Chamber Permanent Pacemaker. In 2011, diagnosed with Carcinoid in Stomach. No Symptoms except weight loss of about 7 kgs in 8 months. Underwent partial Gastrectomy in June 2011. Again it has recurred now in March 2013. My present Sr. Gastrin level is 2445 & Sr. Chromogranin-A is 645. No metastasis as per Dotonac PETCT. IHC (Ki-67) is less than 2%. Is is a cancerous tumor. What is the medication for reducing the growth of tumor / Sr. Gastrin & Chromogranin-A levels and also what is the medication for controlling / curing the growth of the tumer.
Also suggest the next course of treatment
Sat, 20 Apr 2013
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Oncologist, Radiation,  's  Response
Hello;
Gastric carcinoid is low grade tumor meaning it is slow growing tumor compared to typical 'carcinoma.' They have long course and are less responsive to traditional anti-cancer therapy like radiotherapy and chemotherapy.

Somatostatin analogues like octreotide LAR have been utilized to reduce the gastrin/hromogranin levels and have been shown to reduce recurrences, yet its use is not routine.
You can discuss with your oncologist regarding this therapy.Another option is wait and watch with periodic DOTA-scan.

Wish you good health.
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Have Anemia, Bradycardia. History Of Carcinoid In Stomach. How To Reduce Tumor Growth?

Hello; Gastric carcinoid is low grade tumor meaning it is slow growing tumor compared to typical carcinoma. They have long course and are less responsive to traditional anti-cancer therapy like radiotherapy and chemotherapy. Somatostatin analogues like octreotide LAR have been utilized to reduce the gastrin/hromogranin levels and have been shown to reduce recurrences, yet its use is not routine. You can discuss with your oncologist regarding this therapy.Another option is wait and watch with periodic DOTA-scan. Wish you good health.