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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Intrahepatic Cholestasis. High Bilirubin, AST/ALT And Alkaline Phosphatase. Reason?

I have an cronic ilness which is called intrahepatic cholestasis . I had this ilness 6 times in last 8 years. Everytimes when i got sick, it lasted about 3 months to get better. I become yellow because of high billirubines. My AST/ ALT and alkaline phosphatase are elevated to levels that are not normal. And i had itchiness which wasunbearable and kept me awake for 3 months everytime. But after 3 months (without using any medicines) i felt better and all the AST/ALT A.P and Billirubine levels became normal. M.Ds said that it happened because of an allergic reaction to a medicine called Klasid. But they cant say why it happened 5 more times. Because i am not taking medicines anymore. Do you have any ideas for that?
Tue, 7 Aug 2012
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Internal Medicine Specialist 's  Response
Dear friend, welcome to HCM,
cholestatic jaundice can be a side effect of many drugs.
if recurrent without exposure to any drugs, may have different causes.
needs an ultrasound/ CT scan, a gastroenterology opinion.
pl. post results of tests done previously.
take care and pl. keep me posted on the progress.
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Have Intrahepatic Cholestasis. High Bilirubin, AST/ALT And Alkaline Phosphatase. Reason?

Dear friend, welcome to HCM, cholestatic jaundice can be a side effect of many drugs. if recurrent without exposure to any drugs, may have different causes. needs an ultrasound/ CT scan, a gastroenterology opinion. pl. post results of tests done previously. take care and pl. keep me posted on the progress.