Hi.....I'm 72 yrs old and was diagnosed with type 1 diabetes at age 69. I've had Sjogren's with systemic manifestations for many years. Ever since being on Novolog (I don't need a basal insulin.....on a low carb diet) I have had bad peripheral swelling in feet, ankles and lower legs. It goes away during the night. The edema has not responded to a diuretic and thorough testing for venous insufficiency and blood clots was negative. I am not overweight and eat a healthy diet. Because I tend to get yeast easily having Sjogren's as well as diabetes I do use diflucan occasionally and have noticed that it reduces the swelling. Any ideas why I'm having such a prolonged edema reaction to novolog or why diflucan would have a positive effect on reducing the edema? Any ideas would be really helpful. The swelling has made it very difficult for me to wear shoes comfortably. I should mention that I do have peripheral neuropathy but have had it for years and it's assumed to be small fiber from Sjogren's. Thank you.