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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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History Of Two Grandparents On Both Sides Diagnosed With Lupus. Chances Of Passing On?

My father just got diagnosed with lupus and is very concerned plus then the doctors are trying to rule out all the other diagnoses that he is getting hit with along with the Lupus diagnoses. Polycythemiavera and cartine transporter deficiency.Plus my son now has two grandparents on both sides my husbands and mine with Lupus, what are his chances?
Tue, 13 Aug 2013
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General & Family Physician,  's  Response
Hello,

Thanks for posting on HCM,

SLE/lupus has a modest recurrence rate in families: 8% of affected patients have at least one first-degree family member (parents, siblings, and children) with SLE. SLE is influenced both by genetic and environment, so saying the chances of your son ending up with SLE are there but to a lesser extend (i.e might not even occur). He may need from year to year to go through check ups to see if early signs of SLE could be identified.

Hope this helps
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History Of Two Grandparents On Both Sides Diagnosed With Lupus. Chances Of Passing On?

Hello, Thanks for posting on HCM, SLE/lupus has a modest recurrence rate in families: 8% of affected patients have at least one first-degree family member (parents, siblings, and children) with SLE. SLE is influenced both by genetic and environment, so saying the chances of your son ending up with SLE are there but to a lesser extend (i.e might not even occur). He may need from year to year to go through check ups to see if early signs of SLE could be identified. Hope this helps