Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Lupus is an autoimmune disease. In this disease, the body’s immune system, mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain and other organs. Based on the clinical features and the laboratory findings, we choose the right therapy. In practise, we use SLEDAI (Systemic Lupus Erythematosis Disease Activity Index), to make a right evaluation of the disease activity. There are a lot of Disease Modyfing Anti Rheumatologic Drugs which can be helpful for this condition, even in Autoimmune Connective Tissue Diseases, for example Plaquenil (Hydroxychloroquine), once or twice per day, a tablet of Colchicine (as antifibrotic, anti inflammatory agent), and other agents like Methotrexate if you have also articular manifestations. If you have SLE with kidney affected we prefer Mycophenolate Mofetil 2 tb in the morning and 2 in the evening. You have to explain better your symptoms for choosing the right medication. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Ilektra Xhafa (Kacareli)