I m concerned about my 40-year-old daughter, married, mother of two. She s a social worker at a local hospital, very involved in her church and seems to have lots of friends. However, she s obsessed with exercising five days a week, has never had a weight issue, fidgets constantly (can t sit or stand still for any length of time), is extremely programmed, and unable to deviate from her schedule without a major meltdown. She has distanced herself from me off and on for several years. I m in the process of moving out of state and arranged to stay with her for 3 nights until my move. Unfortunately, I needed to change my schedule and mentioned I needed to stay an additional night and she went crazy! She said I was, disrupting her family s schedule. I ve done nothing to disrupt anything, knowing how perfectionist she is about her kids, house, schedule, etc. On the contrary, I ve been attentive to my grand children, and have helped her where I can this week. I should mention that I ve carefully avoided pushing myself on her, knowing how busy she is and letting her take the lead. This is the second time in two years that she has been disrespectful to me and I m wondering if this could be a symptom of an illness. My younger daughter was diagnosed with MS 18 months ago and also had mood swings until she began treatment, but nothing this drastic. I have generalized anxiety and have taken medication for it for 20 years, so I understand the OCD that s going on with her. Tonight s episode was so unlike her and she said her blood pressure shot up during her workout and it was because of her anxiety over me disrupting her family. I appreciate any insight you can offer.